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While this association is not solely attributable to BDNF, the neurotrophin pathway is a leading mechanistic candidate

& Ovize, M

S.|Widmer, H

The addition of NAC to pirfenidone did not significantly affect the safety and tolerability profile of pirfenidone, but it did not appear to confer further benefits in terms of forced vital capacity, although it must be acknowledged that the study was underpowered to demonstrate a meaningful difference

But with age, like many other functions, this antioxidant production can slow down and leave cells more susceptible to harmful free radicals
