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Description
GSTs are involved in phase II metabolism, catalyzing the conjugation of soluble glutathione with reactive intermediates produced during the bioactivation of procarcinogens and detoxification of carcinogens [2]

2ce), indicating that either DEG treatment for 6 h is insufficient to modify the OGDHc-E2, or that exogenous glutarate preferentially alters the PDHc, as previously reported 9
Wienecke S
Jahoor, F
PMID: 31 BrownMAssenFPLeithnerAAbeJSchachnerHAsfourGet al

Moreover, microglia, the predominant immune cells found in the brain, along with astrocytes and oligodendrocytes, albeit to a lesser degree, are linked to the degeneration of neurons in PD (Badanjak et al., 2021