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It was also found to induce Th2 polarization, characterized by local and systemic production of IL-13 and IL-5

doi: 10.3945/jn.108.095638

Phelan [email protected] This article was submitted to Molecular Innate Immunity, a section of the journal Frontiers in Immunology Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

Preclinical studies of anti-FR TS inhibitors including CB300638 and ONX-0801 have demonstrated anti-tumor effect in FR-expressing tumors 15,16

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