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Similar to the ANLS hypothesis, the AMLS model proposes that when the brain is in crisis due to infection, energy flow in brain metabolism is shifted away from the neurons, and shunted toward the microglia (see Figure 2)
Such an approach achieves relevant plasma concentrations without multiple-day oral supplementation and avoids the risk of supratherapeutic antipsychotic plasma concentrations caused by a loading dose
Hypoxia-inducible factor prolyl hydroxylase 2 has a high affinity for ferrous iron and 2-oxoglutarate
G., Agerholm, I., Byriel, L., Fedder, J
Glutathionylation substantially alters the functionality of enzymes, receptors, structural proteins, transcription factors, and transport proteins
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