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Notably, the results demonstrated that UA exerts its effects by downregulating microtubule-associated proteins 1A/1B light chain 3B and Lysosomal-associated membrane protein 1 expression, without significantly altering PINK1 and Parkin protein levels (36)

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They also serve an essential role in cellular activity, acting as coenzymes in various catabolic and anabolic enzymatic activities

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In addition, glutaminase inhibition had no effect on the bioenergetics of the primary CLL cells

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