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in hepatocellular carcinoma, GPX4 deficiency-induced ferroptosis triggers tumor-suppressive immune responses through PD-L1 upregulation and HMGB1-mediated MDSC infiltration [134, 135]

Penning TM (2017) Aldo-keto reductase regulation by the Nrf2 system: implications for stress response, chemotherapy drug resistance, and carcinogenesis

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This includes comparing the affected side with the unaffected one to detect any asymmetries