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It intervenes continuously to regenerate glutathione from GSSG in the presence of NADPH, therefore, prevents cellular loss of glutathione.[57] Patel et al .,[90] reported statistically significant reduction in GSHPX concentrations of 19.41 ng/l and 85.21 ng/l in GCF and serum after non-surgical periodontal therapy, respectively

doi: 10.1016/j.lfs.2021.119529 93 WangJSongYWangQKralikPMEpsteinPN

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Given that this study examined the short-term effects of N-acetylcysteine, it may be possible to gain a deeper understanding of its effects through long-term studies on this substance

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