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144 Similarly, Pien Tze Huang, a traditional Chinese medicine, also exhibits protective effects against APAP-induced liver injury by significantly reducing levels of NLRP3 inflammasomes and proinflammatory cytokines

Vanhove, K

Melatonin in regulation of inflammatory pathways in rheumatoid arthritis and osteoarthritis: involvement of circadian clock genes

[DOI] [PMC free article] [PubMed] [Google Scholar] 16.COVID-19 Rapid Guideline: Managing the Long-Term Effects of COVID-19

Its prevalence has risen dramatically since 1980, when it was a perplexing and sporadically-observed disease as first reported by Ludwig and colleagues (1), to a current estimated 25% global prevalence.(2) NAFLD represents the leading cause of chronic liver disease and is the second leading indication for liver transplantation in the United States.(3) Its rise parallels the obesity epidemic and is attributed to the concomitant rise in the prevalence of type 2 diabetes and metabolic syndrome
