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This bidirectional NO modulation contributes to its vascular protective effects

Lin, B., Li, R., Handley, T., Wade, J.D., Li, W., and OBrien-Simpson, N.M., ACS Infect

MuSC Proliferation In aged skeletal muscle, NNMT overexpression is linked to impaired NAD+ salvage, dysregulated SIRT1 activity, and increased muscle stem cell (MuSC) senescence