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The SURPASS-CVOT trial (NCT04255433) will assess the cardiovascular safety of tirzepatide compared to dulaglutide in people with T2D and established atherosclerotic disease [111]

127 In skeletal muscle, TFEB supports mitochondrial homeostasis by activating mitophagy-related genes such as PINK1, PRKN , and BNIP3 , which are essential under metabolic or exercise-induced stress

Violin and box plots were generated using Prism 10 (GraphPad Software, San Diego, CA)

[Palmer, R.F

Ensure adequate intake (500-1000 mg daily) during the healing period

This study was supported by the Natural Science Foundation of Jilin Province (NO YDZJ202301ZYTS434, NO YDZJ202201ZYTS007) and the Jilin Provincial Development and Reform Commission Project (2023C037-4)