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Morreale de Escobar et al

If you dont have healthy bile composition or bile flow, you may end up with: Vitamin D and K deficiencies which may affect bone health Vitamin D and A deficiencies which may affect immune health Vitamin E deficiency and lower antioxidants Increased dietary oxalate absorption, which may cause mineral deficiencies such as zinc, magnesium, and iron 14 Deficiencies in these minerals have their own set of consequences Constipation Fatty liver High cholesterol Sleep issues Poor detoxification Symptoms of excess estrogen such as PMS, PCOS, or endometriosis SIBO 3,6 Acid reflux that doesnt improve with antacids is typically bile reflux Increased risk of gallstones Gallbladder Dysfunction Increases SIBO Risk The small intestine is typically not home to many microbes

GSH depletion is also strongly associated with aging

Skin color independent assessment of aging using skin autofluorescence

Fortunately, there are several ways to support and enhance natural glutathione production and function

Alpha-melanocyte stimulating hormone: An emerging anti-inflammatory antimicrobial peptide