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This process often includes the addition of mannitol , a stabilising agent that helps protect the peptide

I went another week or so, and four days before my second vaccination my lungs were great

However, to date, oligonucleotide therapeutics are still facing some technological obstacles, such as how to achieve efficient oligonucleotide delivery to target organs or tissues, how to overcome off-target interactions [4952], and how to address the sequence- and chemistry-dependent toxicity and saturation of endogenous RNA processing pathways [53, 54]

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[DOI] [PMC free article] [PubMed] [Google Scholar] 27.Xue XC, et al