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However, the administered NA dose was based on efficiency in hypercholesterolemia studies, therefore, an optimal NA dose for mitochondrial myopathy has to be determined, especially considering that another study found an association between metabolites of excess NA, 2PY, and 4PY, and cardiovascular disease (CVD) 245

In summary, the results of clinical trials and observational studies are consistent with the view that cobalamin plays an important role in cognition, but that its effects may be more noticeable in certain subgroups of the population

Frequency depends on your goals and individual needs

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In our clinic, we use a highly absorbable form Vitamin B12 called methycobalamin

Pre-schedule follow-up labs and dose intervals based on your symptoms, not just textbook timelines
