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Volume 56

556 Consequently, researchers believe that HIF-1 may serve as a mechanism for cells to rapidly respond to acute hypoxia, whereas HIF-2 may be more relevant in chronic hypoxic responses

AAVs, notably AAV2, are less immunogenic, non-pathogenic, and particularly effective in transfecting RGCs (276278)

In recent research, scientists found that GSH, a powerful antioxidant responsible for detoxifying cells, is significantly depleted in individuals with T2DM, especially those with microvascular complications (Lutchmansingh FK et.al., 2018)

It is related to AhpF , a alkyl hydroperoxide reductase

however, insufficient efficacy data support this recommendation