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It suggests the mechanism is not uniform across all cell types and adds a layer of complexity that earlier research did not capture

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[DOI] [PMC free article] [PubMed] [Google Scholar] 23.Premuzic Mestrovic I., Smoday I.M., Kalogjera L., Krezic I., Zizek H., Vranes H., Vukovic V., Oroz K., Skorak I., Brizic I., et al

WangDWuJLeSWangHLuoJLiRet alOltipraz, the activator of nuclear factor erythroid 2-related factor 2 (Nrf2), protects against the formation of BAPN-induced aneurysms and dissection of the thoracic aorta in mice by inhibiting activation of the ROS-mediated NLRP3 inflammasome