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In general, histone modifications are associated with changes in stress-induced gene regulation (Guo et al., 2017), and the members of HDA subfamily share sequence homology in the HDAC domain and require the Zn 2+ cofactor for deacetylase activity (Yang and Seto, 2007

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ZhangSLiMWangJZhouYDaiPZhaoMet alNIR-Triggered On-Demand Nitric Oxide Release for Enhanced Synergistic Phototherapy of Hypoxic Tumor

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We also excluded participants with a history of knee replacement at either baseline or follow-up