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Differences in steroid 5 alpha-reductase iso-enzymes expression between normal and pathological human prostate tissue

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GLP-1 RAs inhibit the TLR4/MYD88/NF-B signaling pathway in renal tubular cells, suppressing NLRP3 inflammasome activation and subsequent IL-1/IL-18 release, which are key drivers of interstitial inflammation (102)