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In a preclinical study, the administration of zonisamide in rats did not affect the serum osteocalcin (a bone formation marker), but it increased the serum pyridinoline (bone resorption marker) levels [113]
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The appropriateness of the continuous use of a daily regimen should be reassessed periodically [413,415]
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Park J, Choi J, Kim D-D, Lee S, Lee B, Lee Y, Kim S, Kwon S, Noh M, Lee M-O, Le Q-V, Oh Y-K (2021) Bioactive lipids and their derivatives in biomedical applications
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