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Proper handling and storage help minimize degradation processes such as hydrolysis, oxidation, and peptide aggregation, which can affect experimental consistency

Elevated levels of lactate in the TME hinder the export of lactate from human CTLs, consequently impeding the proliferation and cytotoxic effects of CTLs

With the development of the first GIP/GLP-1 co-agonist, tirzepatide, there has been an exponential increase in the effectiveness of incretin-mimetic pharmacological therapy for weight control in obese patients with and without diabetes

Pharmacol Biochem Behav 52:683687 Inui T, Shimura T (2014) Delta-opioid receptor blockade in the ventral pallidum increases perceived palatability and consumption of saccharin solution in rats

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