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Life Sci 74:563572 Reiter RJ, Tan DX, Mayo JC, Sainz RM, Leon J, Czarnocki Z (2003) Melatonin as an antioxidant: biochemical mechanisms and pathophysiological implications in humans
In mice, the authors demonstrated that PHGDH interacts with phosphofructokinase, and the loss of this interaction increases flux through hexosamine biosynthesis ( V 3 sialylation, which facilitates tumor metastatic activity

[DOI] [PMC free article] [PubMed] [Google Scholar] 97.Ferraris C., Meroni E., Casiraghi M.C., Tagliabue A., Giorgis V.D., Erba D

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Formulation & Skin-Delivery Considerations (No Dosing Guidance) Carriers: Liposomes and other vesicular systems may improve skin retention/penetration of hydrophilic peptides like GHK-Cu (PMC)
