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The classical chemical modification of DNA and histones in this regard is methylation, and the methyl groups required for such methylation come from the diet and one-carbon metabolism

Cobalamin deficiency: Effect on homeostasis of cultured human astrocytes

Generally, people who have a B5 deficiency often have other deficiencies at the same time

Lipincott Williams & Wilkins, a division of Wolters Kluwer Health, 327-335, 2014

It also serves as a reducer, conjugates to drugs to make them more soluble in water
