melanotic macules on lips Brown spots, especially the lips, can be alarming to some. In some instances it can indicate rare oral mucosal melanoma, however in this case it was a non-cancerous labial macule. Mystery behind labial and oral
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Cristaldi, V

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The enzyme 3-hydroxysteroid dehydrogenase (3-HSD) is a key branch-point enzyme because it converts 5 steroids such as pregnenolone and DHEA into their 4 counterparts, including progesterone and androstenedione
