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The AHCY gene is located on chromosome 20q11.22 and is composed of 17 exons that generate six alternatively spliced mRNAs encoding three distinct proteins isoforms of 432 amino acids (isoform 1), 404 amino acids (isoform 2), and 434 amino acids (isoform 3)

An interesting structural strategy observed is that the CBM-containing peptides adopted different conformations to fit in each of the binding pockets, something that could only be acquired in the context of IDRs

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doi: 10.1016/j.ejphar.2025.177573

10.1021/acsnano.2c03222 85 ZhongX