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Nat Rev Gastroenterol Hepatol 2024;21:136-7

It is crucial to maintain a healthy redox state of pancreatic -cells, as their ability to secrete insulin in response to glucose is dependent on intracellular thiols [30]

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Insulin growth factor-based dosing of growth hormone therapy in children: a randomized, controlled study

Functionally, it is vital for the control of immune responses via neural signaling

SS-31 (elamipretide) , a mitochondria-targeted peptide that stabilizes cardiolipin to support energy production, became the first FDA-approved mitochondrial therapeutic in 2025, though only for the rare Barth syndrome, with the brain rationale still mechanistic and no cognitive trials