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Declarations Authors contributions Wrote the manuscript: Nguyen TL, Durn RV Secured funding: Durn RV Availability of data and materials Not applicable

This may occur due to rapid detoxification processes in the body

Enhancing tissue repair after intense physical activity or injury

The combination of the NMDAR antagonist MK-801 (100 mM) with different antiestrogens (TAM, OHTAM, and EDX) at a concentration of 5 mM, strongly reduces melanoma cell proliferation and viability, even more than the observation made when the cells were treated only with MK-801 (500 mM)

Such up-to-date computational models include Bhasin, et al

However, these compounds have been confirmed to have significant neuroprotective and preventive activity in OIPN preclinical and clinical data [186, 187]
