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Additional trials of SYNERGY-NASH (NCT04166773) will look into tirzepatide's effectiveness in nonalcoholic steatohepatitis (NASH) and its effect on those who are obese and have heart failure with maintained ejection fractions

The patience required during tirzepatide titration pays dividends in the months that follow

Patients taking tirzepatide should call 911 or seek emergency care immediately if they experience large-volume bright red blood per rectum, passage of maroon or black tarry stools (melena), or blood in stool accompanied by hemodynamic instability

Curbing the Obesity Epidemic: Should GLP-1 Receptor Agonists Be the Standard of Care for Obesity