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Increase to 5 mg: After 4 weeks, increase the dose to 5 mg once weekly

Table of Contents Understanding the GLP-1 Mechanism Ozempic and Mounjaro: What Sets Them Apart Integrating GLP-1 Agonists into Clinical Practice Addressing Patient Expectations and Concerns Understanding the GLP-1 Mechanism GLP-1 receptor agonists mimic the natural incretin hormone, stimulating insulin secretion while inhibiting glucagon release in a glucose-dependent manner

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Additionally, Tesofensine also affects the reward pathways in the brain, making it less rewarding to eat food, leading to further decrease in food intake