glp-1 drugs and depression Transformation 2.0: The RAs as Psychiatric Medications? The risk of depression, anxiety,

Targeted ablation of glucosedependent insulinotropic polypeptideproducing cells in transgenic mice reduces obesity and insulin resistance induced by a high fat diet

Based on the current evidence, GLP-1RAs should be considered alongside other guideline-directed medical therapies for HFpEF when indicated for T2D or obesity

Im not sure of the exact latest percentages, but the relative ranking (Japan low vs peers) holds

Yu X, Tang H, Huang L, Yang Y, Tian B, and Yu C

2022;10(4):e00962

Another DPP4 inhibitor Des-fluoro-sitagliptin was also reported to decrease the accumulation of M1 macrophages in Gck +/- mice, a -cellspecific glucokinase haploinsufficient (Gck+/) diabetic model (33)