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Efficacy of the GLP-1 receptor agonist, semaglutide, in abstinence from illicit and nonprescribed opioids in an outpatient population with treatment-refractory OUD: a randomized, double-blind, placebo-controlled clinical trial protocol

Always pair them with protein, fat, or ideally both

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The ACHIEVE-1 trial involved 559 adult participants treated with orforglipron at 3 mg, 12 mg, or 36 mg, compared to placebo, over a 40-week duration

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