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Semaglutide at a dose of 2.4 mg is currently the most effective GLP-1 receptor agonist for weight reduction

Most procedures are minimally invasive and include careful preparation and follow-up

The pre-proglucagon system constitutes interesting candidates as potential targets for new anti-obesity drugs

Increases of roughly up to ~30 minutes above an individual's 7-day baseline showed little change in recovery metrics, but larger jumps in training load were associated with higher minimum heart rate and persistently lower HRV

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Higher-risk patients include those in the dose-escalation phase, those with nausea, vomiting, bloating, abdominal pain, early satiety, or reflux symptoms, those on higher doses with GI side effects, and those with known gastroparesis or other conditions that slow gastric emptying