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NEURODEGENERATIVE DISEASES: ALZHEIMERS AND PARKINSONS DISEASES An analysis of the mechanisms of action of GLP-1 and GLP-1RAs indicates that these compounds, by activating GLP-1R, modulate the molecular and cellular changes, and influence the shared processes that determine the phenomenology of neurodegenerative diseases (NDD) and a number of other brain diseases [36]

28 This imbalance may allow maximisation of effect on the GIP pathway while minimising GLP-1-related tolerability issues

PMID: 29364588

Lilly reported a dropout rate of 18.2% for patients who got the drug compared with 4% in the placebo group

[DOI] [PubMed] [Google Scholar] 70.Talley NJ, Verlinden M, Jones M
