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Conclusions GLP-1RAs had a neutral effect on the composite cardiovascular outcomes but reduced composite kidney events in the patients with advanced DKD compared with DPP-4is.

The primary concern with elevated bilirubin in semaglutide-treated patients is distinguishing benign causes (Gilbert's syndrome, hemolysis) from drug-induced...

Here we review evolving concepts of incretin action, focusing predominantly on GLP-1, from discovery, to clinical proof of concept, to therapeutic outcomes

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