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Description
Abbreviations ADVANCE: action in diabetes and vascular disease AMI: acute myocardial infarction BID: twice daily bpm: beats per minute CI: confidence interval CVOT: cardiovascular outcome trial ELIXA: Evaluation of LIXisenatide in Acute coronary syndrome FIGHT: Functional Impact of GLP-1 for Heart Failure Treatment GLP-1 RA: glucagon-like peptide-1 receptor agonist HF: heart failure HR: heart rate LAR: long-acting release LEADER: Liraglutide Effect and Action in Diabetes: Evaluation of Cardiovascular Outcome Results LIVE: Effect of LIraglutide on left VEntricular function in chronic heart failure patients with and without type 2 diabetes LS: least squares PK: pharmacokinetic QD: once daily QW: once weekly SE: standard error T2DM: type 2 diabetes mellitus References Inzucchi SE, Bergenstal RM, Buse JB, Diamant M, Ferrannini E, Nauck M, Peters AL, Tsapas A, Wender R, Matthews DR

When semaglutide is given at high doses without a slow buildup, it can cause significant nausea and vomiting

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Thevenet, J

For efficient knockdown of the TGF- and DPP4 genes, pooled siRNAs (siRNA1 and siRNA2) targeting each gene were used

For more details, please refer to the manual: Handling and Storage of Synthetic Peptides References Hargrove et al (1995) Glucose-dependent action of glucagon-like peptide-1 (7-37) in vivo during short- or long-term administration
