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Ongoing research may teach us more about whether GLP-1 receptor agonists can influence Alzheimers disease progression or neurodegenerative risk

A combined effect that is bigger than just decreasing calories is thought to be at play when looking at the effects of activating the GLP-1 receptor.[ref] In overweight adults aged 45+, a 4-year-long study using semaglutide for weight loss also prevented HbA1c from rising over time, which was seen in the placebo arm
For you as someone considering or using these medications, the practical takeaway is straightforward

"Safety and Efficacy of Omarigliptin (MK-3102), a Novel Once-Weekly DPP-4 Inhibitor for the Treatment of Patients With Type 2 Diabetes"

And are they worth trying

New GLP-1 agonist guidance FAQs and patient information We've developed FAQs and patient information for clinicians to use when talking to patients using GLP-1/GIP receptor agonists
