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Beyond their metabolic effects, GLP-1 RAs have demonstrated cardiovascular and renal benefits in large outcome trials, including reductions in major adverse cardiovascular events (MACE) and attenuation of albuminuria progression ( Table 1 , renal eligibility criteria across landmark GLP-1 RA cardiovascular and kidney outcome trials consistently excluded dialysis-dependent patients, resulting in a persistent lack of randomized evidence in this high-risk population

However, alcohol can worsen gastrointestinal side effects common with this drug class and can affect blood sugar control, so once the medicine is licensed, patients should follow the prescribers specific guidance

Your provider can check levels and advise supplementation if appropriate

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Finally, PubMed (www.ncbi.nlm.nih.gov/pubmed) was searched under all 28 drugs AND separate keywords including eye, vision, cornea, conjunctiva, sclera and contact lens to try to identify any peer-reviewed publications (including any case reports) that reported on the possible ocular effects of these drugs

Remember to get your fiber through whole foods (e.g., fruits, veggies, legumes, whole grains) as well