glp 1 agonist 종류 GLP-1 기반 차세대 항당뇨병제는 누구? < 내분비/신장 < 학술 < 기사본문 당뇨약 이야기 (3) - GLP-1
Description
520 The anti-tumor effect of liraglutide is related to its inhibition of the PI3K/Akt signaling pathway, as the activation of Akt is crucial for promoting cell survival and proliferation, and liraglutide can inhibit this process in a dose-dependent manner
Moreover, chronic treatment with liraglutide showed an increase in stem cell proliferation and differentiation into mature neurons in APP/PS1 mice and controls at all ages, which may have beneficial effects in neurodegenerative disorders like AD (168)
GLP1 RA treatment patterns among type 2 diabetes patients in five European countries
Integration of population exposure-response and physiological based pharmacokinetic modeling approaches to evaluate gastric-emptying induced drug interaction risks for dulaglutide
doi: 10.1210/clinem/dgab408 [DOI] [PubMed] [Google Scholar] 201
[46] This activation reduces the production of reactive oxygen species (ROS) and mitigates endoplasmic reticulum (ER) stress
