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The FDA's decision to grant orforglipron a Commissioner's National Priority Review Voucher further accelerated the regulatory timeline, potentially compressing the standard 10-12 month review period to as little as 1-2 months

LFD control slides are set to baseline of 1 to account for resident Kupffer cells (dark stained spots disperse equally between hepatocytes)

Its classified as a teratogen , which means it has the potential to cause birth defects or disrupt normal fetal development if taken during pregnancy

*Retatrutide is a novel medication that acts on GLP1, GIP, and Glucagon receptors

Tirzepatide: The Basics Tirzepatide works on two hormone pathways instead of one (GLP-1 and GIP, making it a dual agonist)