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For a patient weighing which drug to start on, the study offers something no earlier comparison has: a view of what each choice actually buys and what it costs across every outcome that matters, from weight and waistline to muscle, heart, kidneys and how a person feels

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Clinical trials for these treatments have consistently highlighted digestion challenges as the most prevalent side effects clinical studies for Wegovy PI, for example, showed 44% of patients suffered nausea (compared to 16% in the placebo group)

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