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doi: 10.1001/jamanetworkopen.2024.13172 146 KimCRossJSJastreboffAMMeekerDFreedmanHKrumholzHMet al

2023;46(Supp 1):S128-S139
These results suggest that the endogenous relevance of LHA GHSR signaling to palatable food-motivated responding is more prominent in females, whereas the opposite is true for LHA GLP-1 signaling

Clinical trials show that gradual dose escalation produces better long-term adherence and more sustainable weight loss than jumping to higher doses immediately
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All treatments significantly elevated the serum levels of kynurenine, but they failed to affect the kynurenine-Trp ratio
