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Xie, W., Huang, H., Deng, X., Gao, D

GLP-1R works through the combination of the endogenous ligand Glucagon-like peptide-1 (GLP-1) or exogenous agonists, which activate multiple intracellular signaling pathways that enhance insulin secretion, inhibit glucagon secretion, protect -cells from apoptosis, delay gastric emptying and increase satiety

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Once opened, most formulations remain stable at these temperatures for 28 days