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doi: 10.1530/JOE-18-0596

Clinical trials show average weight loss of 15-22% over 68 weeks on semaglutide alone, with some patients reaching 25%+ loss

They then administered 40 mcg of semaglutide twice weekly and 0.05 mg/Kg of psilocybin daily, either alone or in combination, and included a control group on a standard diet

Because sublingual bioavailability is lower than injection bioavailability, the actual milligram dose in the drops is higher than the equivalent injectable dose