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Comparative Clinical Evidence: Efficacy and Duration Clinical trial data separates these agents by efficacy magnitude and durability

Zhang J, Tang H, Deng R, Wang N, Zhang Y, Wang Y, et al

Following each 8-week phase, a two-week washout period was implemented before participants crossed over to the alternate condition

The key to long-term success with these treatments is consistencyboth in taking your medication and in maintaining a balanced diet and exercise routine
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The highest dose of orforglipron helped patients lose on average 10.5% of their weight, or 22.9 pounds, on average at 72 weeks, compared to 2.2% weight loss among those who took a placebo
