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Increased Heart Rate Taking semaglutide may lead to a slight increase in heart rate typically by two to three beats per minute, based on trials sponsored by Novo Nordisk using 0.5 and 1 mg doses of semaglutide

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Semaglutide, a glucagon-like peptide-1 GLP-1 agonist, induces weight loss through central mechanisms by delaying gastric emptying, increasing satiety, decreasing appetite and reducing energy intake [11- 13]