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If youre on a journey toward better health whether that means balancing blood sugar, managing weight, or just feeling more energized theres a hormone youll want to know about: GLP-1 (short for Glucagon-like Peptide-1)

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In the first trial, lixisenatide 20 g QD (n = 46) and liraglutide 1.2 (n = 44) and 1.8 mg QD (n = 46) were compared following 8 weeks treatment in 142 subjects with T2DM not adequately controlled with insulin glargine with or without metformin [17]

These drugs, known as GLP-1 agonists, include semaglutide and tirzepatide

Systematic searches were conducted in PubMed/MEDLINE, Embase, Cochrane Library, Web of Science, and ClinicalTrials.gov from database inception through 31 May 2025