glp 1 drugs brands GLP-1 supplements are everywhere—but do they actually work? As demand for weight-loss grows, companies are cashing in on products that claim to support GLP-1 goals, often with little oversight. Tap the GLP-1 Medications | Daniel Stark

Jazmin Aguilera: It sounds like a pretty big downside

[DOI] [PubMed] [Google Scholar] 272.Tahrani, A

The risk for thyroid cancer over a maximum of 8 years of follow-up did not differ between GLP-1 medication users and adults using an SGLT2 inhibitor, DPP-IV inhibitor or sulfonylurea, though GLP-1 users did have a higher thyroid cancer risk during the first year of therapy

The maximum weight reduction effect ranged from 4.25 kg (Liraglutide) to 22.6 kg (Retatrutide)

A GLP-1 agonist might be for you if you need an adjuvant for lifestyle modifications in losing weight or improving metabolic parameters, like blood glucose

On the other hand, GLP-1 RAs were found to alter the gastric/small bowel motility and appetite/satiation via central or parasympathetic (vagal-mediated) pathways, leading to an increased incidence of retained gastric contents (RGCs) with the associated aspiration risk during the perioperative period [6,7,8]