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Because of its dual mechanism, tirzepatide often produces greater average weight loss and stronger blood sugar improvements in many patients

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One notable risk is gastroparesis (stomach paralysis), which appears to be a severe side effect of the drug

Phentermine is related to the amphetamines, and there has been historical concern that phentermine might exhibit potential to cause serotonin syndrome or cardiovascular or pulmonary effects when combined with serotonergic agents
