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doi: 10.1177/1060028017689878 64 Pharmacological profile, efficacy and safety of lixisenatide in type 2 diabetes mellitus

[DOI] [PubMed] [Google Scholar] 236.Orskov C., Wettergren A., Holst J.J

Multiple cis-acting domains mediate basal and adenosine 3',5'-monophosphate-dependent glucagon gene transcription in a mouse neuroendocrine cell line

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348 Similarly, in human chondrocytes stimulated by TNF, GLP-1 analogs (such as liraglutide) showed an anti-catabolic effect, reducing the mRNA expression of MMP-3, MMP-13, and ADAMTS5

Weight loss can enhance insulin sensitivity and improve glycemic control in individuals with diabetes, reducing the need for higher doses of medication and potentially leading to diabetes remission in some cases