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The manufacturers will point to the modest absolute risk and the observational nature of the data

Blood sugar levels may rise, especially in people with type 2 diabetes

We dont know how the medicines interact with the human body

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It is linked to elevated levels of fibrinogen and C-reactive protein, diabetes, insulin resistance, dyslipidemia, and hypertension, all of which raise the risk of CVD events ( It is less evident how GLP-1 agonists directly affect arrhythmias, some studies suggest they may reduce frequency of arrythmias because their favorable effects on metabolism and over all cardiovascular health

Thorin: Mice broken up into 2 groups, one on a GLP-1, the other was not