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Effect of caloric restriction or aerobic exercise training on peak oxygen consumption and quality of life in obese older patients with heart failure with preserved ejection fraction: a randomized clinical trial

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Further corroborating the potential protection against GRK/arrestin-mediated desensitization via continuous trafficking between the plasma membrane and the cytoplasmis another study showing that the interaction of arrestin2 with the GLP-1R is very transient, i.e., the GLP-1R is a class A GPCR in terms of arrestin binding [37]