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Source: University of Gothenburg A specific group of nerve cells in the brain stem appears to control how semaglutide affects appetite and weight without causing nausea

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Because ER agonists can enhance cell proliferation in the adult hippocampus (Mazzucco et al., 2006), it therefore seems possible that TAM blockade of ER could suppress proliferation

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Your body is still adapting to semaglutide, and a slightly higher dose might even help you get into the therapeutic range faster